UPF3B

gene product
HUPF3B, MRX62, RENT3B, UPF3X
This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. The encoded protein is one of two functional homologs to yeast Upf3p. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein binds to the mRNA and remains bound after nuclear export, acting as a nucleocytoplasmic shuttling protein. It forms with Y14 a complex that binds specifically 20 nt upstream of exon-exon junctions. This gene is located on the long arm of chromosome X. Two splice variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
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69 antibodies from 21 providers.

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AntibodyRefsTypeAVIWBELICCIPIHCFC
Abnova Corporation
2 antibodies
Novus Biologicals
5 antibodies
Atlas Antibodies
3 antibodies
Invitrogen Antibodies
3 antibodies
NovoPro Bioscience Inc.
1 antibody
Proteintech Group
1 antibody
LifeSpan BioSciences, Inc.
18 antibodies
antibodies-online
12 antibodies
GeneTex
3 antibodies
Aviva Systems Biology
2 antibodies
OriGene
2 antibodies
NSJ Bioreagents
1 antibody
Bethyl Laboratories
2 antibodies
ProSci
2 antibodies
Boster Biological Technology
1 antibody
Acris Antibodies GmbH
1 antibody
St John's Laboratory
1 antibody
Sigma-Aldrich
4 antibodies
Creative Diagnostics
2 antibodies
MyBioSource
2 antibodies
Biorbyt
1 antibody