Tissue expression
Cell line expression

UPF3B

gene product
HUPF3B, MRX62, MRX82, RENT3B, UPF3BP1, UPF3BP2, UPF3BP3, UPF3X 
This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. The encoded protein is one of two functional homologs to yeast Upf3p. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein binds to the mRNA and remains bound after nuclear export, acting as a nucleocytoplasmic shuttling protein. It forms with Y14 a complex that binds specifically 20 nt upstream of exon-exon junctions. This gene is located on the long arm of chromosome X. Two splice variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
More gene data

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105 antibodies from 23 providers.

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AntibodyRefsTypeWBELICCIPIHCFC
Proteintech Group
1 antibody
Abnova Corporation
2 antibodies
LifeSpan BioSciences, Inc.
19 antibodies
Atlas Antibodies
3 antibodies
Invitrogen Antibodies
12 antibodies
Novus Biologicals
5 antibodies
antibodies-online
26 antibodies
Cusabio Biotech Co., Ltd
4 antibodies
NovoPro Bioscience Inc.
1 antibody
Wuhan Fine Biotech Co., Ltd.
1 antibody
GeneTex
3 antibodies
Aviva Systems Biology
2 antibodies
OriGene
2 antibodies
NSJ Bioreagents
1 antibody
Biorbyt
6 antibodies
Boster Biological Technology
1 antibody
Bethyl Laboratories
2 antibodies
ProSci
2 antibodies
Acris Antibodies GmbH
1 antibody
MilliporeSigma / Merck KGaA
4 antibodies
Creative Diagnostics
2 antibodies
MyBioSource
2 antibodies
Creative Biolabs
3 antibodies