FBLN5

gene product
ARMD3, DANCE, EVEC, UP50
The protein encoded by this gene is a secreted, extracellular matrix protein containing an Arg-Gly-Asp (RGD) motif and calcium-binding EGF-like domains. It promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. It is prominently expressed in developing arteries but less so in adult vessels. However, its expression is reinduced in balloon-injured vessels and atherosclerotic lesions, notably in intimal vascular smooth muscle cells and endothelial cells. Therefore, the protein encoded by this gene may play a role in vascular development and remodeling. Defects in this gene are a cause of autosomal dominant cutis laxa, autosomal recessive cutis laxa type I (CL type I), and age-related macular degeneration type 3 (ARMD3). [provided by RefSeq, Jul 2008]
More gene data

Featured antibodies

Antibodies

 

Filters

Antibodypedia Validation Initiative

Validation method

Application

Reference

Provider

Host

Reactivity

Antibody type

Conjugate

  or   Clear
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider
Validated within AVI
Eligible for validation within AVI
308 antibodies from 33 providers.

Antibody properties

Applications

or Cancel
AntibodyRefsTypeAVIWBELICCIPIHCFC
antibodies-online
99 antibodies
Proteintech Group
2 antibodies
NovoPro Bioscience Inc.
4 antibodies
Novus Biologicals
8 antibodies
GeneTex
5 antibodies
R&D Systems
1 antibody
LifeSpan BioSciences, Inc.
44 antibodies
Acris Antibodies GmbH
4 antibodies
Biorbyt
11 antibodies
Affinity Biosciences
3 antibodies
Abnova Corporation
8 antibodies
OriGene
5 antibodies
Invitrogen Antibodies
7 antibodies
Abgent
4 antibodies
St John's Laboratory
6 antibodies
ProSci
4 antibodies
Antibodies.com
1 antibody
Aviva Systems Biology
3 antibodies
Everest Biotech
1 antibody
NSJ Bioreagents
1 antibody
MyBioSource
12 antibodies
Atlas Antibodies
2 antibodies
RabMAbs
4 antibodies
Creative Biolabs
2 antibodies
Abbkine Scientific Co.Ltd.
1 antibody
Arigo
1 antibody
Abbiotec
4 antibodies
United States Biological
42 antibodies
Sigma-Aldrich
3 antibodies
Creative Diagnostics
2 antibodies
Abbexa
1 antibody
EMD Millipore
1 antibody