Tissue expression
Cell line expression
Protein structure
RBM8A
RNA binding motif protein 8ABOV-1A, BOV-1B, BOV-1C, RBM8, RBM8B, Y14, ZNRP
This gene encodes a protein with a conserved RNA-binding motif. The protein is found predominantly in the nucleus, although it is also present in the cytoplasm. It is preferentially associated with mRNAs produced by splicing, including both nuclear mRNAs and newly exported cytoplasmic mRNAs. It is thought that the protein remains associated with spliced mRNAs as a tag to indicate where introns had been present, thus coupling pre- and post-mRNA splicing events. Previously, it was thought that two genes encode this protein, RBM8A and RBM8B; it is now thought that the RBM8B locus is a pseudogene. There are two alternate translation start codons with this gene, which result in two forms of the protein. An allele mutation and a low-frequency noncoding single-nucleotide polymorphism (SNP) in this gene cause thrombocytopenia-absent radius (TAR) syndrome. [provided by RefSeq, Jul 2013]
Top validated antibodies |
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Proteintech Group | 14958-1-AP | 4 references | Polyclonal |
WB
EL
ICC
IP
IHC
|
|
Invitrogen Antibodies | 14958-1-AP | Polyclonal |
WB
ICC
IP
IHC
OA
|
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Novus Biologicals | NBP1-88376 | 2 references | Polyclonal |
WB
ICC
IHC
|
|
Biorbyt | orb1727063 | Recombinant |
WB
ICC
IP
IHC
FC
|
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GeneTex | GTX25828 | Monoclonal |
WB
EL
ICC
IP |
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Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider