BRCA2

gene product
BRCC2, FACD, FAD, FAD1, FANCD, FANCD1, XRCC11
Inherited mutations in BRCA1 and this gene, BRCA2, confer increased lifetime risk of developing breast or ovarian cancer. Both BRCA1 and BRCA2 are involved in maintenance of genome stability, specifically the homologous recombination pathway for double-strand DNA repair. The BRCA2 protein contains several copies of a 70 aa motif called the BRC motif, and these motifs mediate binding to the RAD51 recombinase which functions in DNA repair. BRCA2 is considered a tumor suppressor gene, as tumors with BRCA2 mutations generally exhibit loss of heterozygosity (LOH) of the wild-type allele. [provided by RefSeq, Dec 2008]
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292 antibodies from 34 providers.

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Antibody
Novus Biologicals
24 antibodies
GeneTex
5 antibodies
Proteintech Group
1 antibody
R&D Systems
1 antibody
OriGene
15 antibodies
antibodies-online
113 antibodies
Affinity Biosciences
2 antibodies
NovoPro Bioscience Inc.
2 antibodies
Biorbyt
17 antibodies
Bioworld Technology, Inc
1 antibody
Bethyl Laboratories
3 antibodies
Aviva Systems Biology
3 antibodies
Acris Antibodies GmbH
5 antibodies
MyBioSource
14 antibodies
Abnova Corporation
2 antibodies
Arigo
2 antibodies
Creative Biolabs
17 antibodies
Invitrogen Antibodies
3 antibodies
Atlas Antibodies
1 antibody
NSJ Bioreagents
1 antibody
St John's Laboratory
3 antibodies
Creative Diagnostics
5 antibodies
ProSci
2 antibodies
Abbiotec
1 antibody
Abiocode, Inc.
1 antibody
Cell Signaling Technology, Inc
1 antibody
United States Biological
14 antibodies
GenWay
8 antibodies
Sigma-Aldrich
3 antibodies
Abbkine Scientific Co.Ltd.
2 antibodies
EMD Millipore
2 antibodies
Abgent
1 antibody
RayBiotech, Inc.
1 antibody