Tissue expression
Cell line expression
Protein structure
NBR1
NBR1 autophagy cargo receptor1A1-3B, CA125, KIAA0049, M17S2
The protein encoded by this gene was originally identified as an ovarian tumor antigen monitored in ovarian cancer. The encoded protein contains a B-box/coiled-coil motif, which is present in many genes with transformation potential. It functions as a specific autophagy receptor for the selective autophagic degradation of peroxisomes by forming intracellular inclusions with ubiquitylated autophagic substrates. This gene is located on a region of chromosome 17q21.1 that is in close proximity to the BRCA1 tumor suppressor gene. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2014]
Top validated antibodies |
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Proteintech Group | 16004-1-AP | 30 references | Polyclonal |
WB
EL
ICC
IP
IHC
FC |
|
Invitrogen Antibodies | 16004-1-AP | Polyclonal |
WB
ICC
IP
IHC
FC
OA |
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Novus Biologicals | H00004077-M01 | 12 references | Monoclonal |
WB
EL
ICC
IEM |
|
NovoPro Bioscience Inc. | 113023 | Polyclonal |
WB
EL
ICC
IP
IHC
FC |
||
antibodies-online | ABIN396674 | 5 references | Monoclonal |
WB
EL
IHC
|
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