AMBP

This gene encodes a complex glycoprotein secreted in plasma. The precursor is proteolytically processed into distinct functioning proteins: alpha-1-microglobulin, which belongs to the superfamily of lipocalin transport proteins and may play a role in the regulation of inflammatory processes, and bikunin, which is a urinary trypsin inhibitor belonging to the superfamily of Kunitz-type protease inhibitors and plays an important role in many physiological and pathological processes. This gene is located on chromosome 9 in a cluster of lipocalin genes. [provided by RefSeq, Jul 2008]

Description

alpha-1-microglobulin/bikunin precursor

Protein family

Mapped to UniProt SWISS-PROT, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, Protein evidence (Ezkurdia et al 2014), Protein evidence (Kim et al 2014)

Chromosome

9:q32 (114060127 - 114078472)

Ensembl ID

ENSG00000106927  (ver. 84.38)

Orthologs

Mouse Ambp: ENSMUSG00000028356

UniProt

P02760

neXtProt

NX_P02760

Human splice variants
Mouse splice variants