AMBP

This gene encodes a complex glycoprotein secreted in plasma. The precursor is proteolytically processed into distinct functioning proteins: alpha-1-microglobulin, which belongs to the superfamily of lipocalin transport proteins and may play a role in the regulation of inflammatory processes, and bikunin, which is a urinary trypsin inhibitor belonging to the superfamily of Kunitz-type protease inhibitors and plays an important role in many physiological and pathological processes. This gene is located on chromosome 9 in a cluster of lipocalin genes. [provided by RefSeq, Jul 2008]

Description

Alpha-1-microglobulin/bikunin precursor

Tissue specificity

Tissue enriched (liver)

Subcell location

Golgi apparatus, Vesicles, Cytosol

Predicted location

Intracellular, Secreted to blood

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Plasma proteins
Predicted intracellular proteins
Predicted secreted proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)

Chromosome

9:q32 (114060127 - 114078328)

Ensembl ID

ENSG00000106927  (ver. 103.38)

Orthologs

Mouse Ambp: ENSMUSG00000028356

UniProt

P02760

neXtProt

NX_P02760

Human splice variants
Mouse splice variants