Tissue expression
Cell line expression
Protein structure
OLIG2
Oligodendrocyte transcription factor 2BHLHB1, bHLHe19, OLIGO2, PRKCBP2, RACK17
This gene encodes a basic helix-loop-helix transcription factor which is expressed in oligodendroglial tumors of the brain. The protein is an essential regulator of ventral neuroectodermal progenitor cell fate. The gene is involved in a chromosomal translocation t(14;21)(q11.2;q22) associated with T-cell acute lymphoblastic leukemia. Its chromosomal location is within a region of chromosome 21 which has been suggested to play a role in learning deficits associated with Down syndrome. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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Proteintech Group | ![]() |
66 references | Polyclonal |
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R&D Systems | ![]() |
38 references | Polyclonal |
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LSBio | ![]() |
Monoclonal |
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Novus Biologicals | ![]() |
43 references | Polyclonal |
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antibodies-online | ![]() |
2 references | Monoclonal |
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