Tissue expression
Cell line expression
Protein structure
CTSH
Cathepsin HACC-4, ACC-5, ACC4, ACC5, CPSB
The protein encoded by this gene is a lysosomal cysteine proteinase important in the overall degradation of lysosomal proteins. It is composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. The encoded protein, which belongs to the peptidase C1 protein family, can act both as an aminopeptidase and as an endopeptidase. Increased expression of this gene has been correlated with malignant progression of prostate tumors. Alternate splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2016]
Top validated antibodies |
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Proteintech Group | 10315-1-AP | 5 references | Polyclonal |
WB
EL
ICC
IHC |
|
R&D Systems | AF1013 | 4 references | Polyclonal |
WB
IP
IHC
|
|
Novus Biologicals | AF1013 | 4 references | Polyclonal |
WB
IP
IHC
|
|
Invitrogen Antibodies | 10315-1-AP | Polyclonal |
WB
ICC
IHC
FC |
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antibodies-online | ABIN2036063 | Polyclonal |
WB
EL
IHC
FC |
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Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider