VHL

gene product
VHL1
Von Hippel-Lindau syndrome (VHL) is a dominantly inherited familial cancer syndrome predisposing to a variety of malignant and benign tumors. A germline mutation of this gene is the basis of familial inheritance of VHL syndrome. The protein encoded by this gene is a component of the protein complex that includes elongin B, elongin C, and cullin-2, and possesses ubiquitin ligase E3 activity. This protein is involved in the ubiquitination and degradation of hypoxia-inducible-factor (HIF), which is a transcription factor that plays a central role in the regulation of gene expression by oxygen. RNA polymerase II subunit POLR2G/RPB7 is also reported to be a target of this protein. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008]
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730 antibodies from 38 providers.

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GeneTex
6 antibodies
antibodies-online
233 antibodies
Biorbyt
26 antibodies
Novus Biologicals
73 antibodies
Invitrogen Antibodies
12 antibodies
Abgent
6 antibodies
NSJ Bioreagents
3 antibodies
Proteintech Group
2 antibodies
Abnova Corporation
10 antibodies
LifeSpan BioSciences, Inc.
117 antibodies
St John's Laboratory
8 antibodies
Bioworld Technology, Inc
2 antibodies
Acris Antibodies GmbH
12 antibodies
Aviva Systems Biology
6 antibodies
Affinity Biosciences
3 antibodies
NovoPro Bioscience Inc.
2 antibodies
ProSci
3 antibodies
Santa Cruz Biotechnology
1 antibody
OriGene
20 antibodies
Everest Biotech
1 antibody
Abbkine Scientific Co.Ltd.
3 antibodies
RabMAbs
3 antibodies
MyBioSource
7 antibodies
Arigo
1 antibody
Atlas Antibodies
2 antibodies
Creative Biolabs
14 antibodies
Abbexa
13 antibodies
Creative Diagnostics
5 antibodies
United States Biological
89 antibodies
Cell Signaling Technology, Inc
2 antibodies
Leading Biology
5 antibodies
RayBiotech, Inc.
2 antibodies
Abiocode, Inc.
1 antibody
Exalpha Biologicals, Inc.
1 antibody
Abbiotec
1 antibody
EMD Millipore
1 antibody
Sigma-Aldrich
4 antibodies