Tissue expression
Cell line expression
Protein structure
SIRT6
Sirtuin 6This gene encodes a member of the sirtuin family of NAD-dependent enzymes that are implicated in cellular stress resistance, genomic stability, aging and energy homeostasis. The encoded protein is localized to the nucleus, exhibits ADP-ribosyl transferase and histone deacetylase activities, and plays a role in DNA repair, maintenance of telomeric chromatin, inflammation, lipid and glucose metabolism. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2016]
Top validated antibodies |
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Novus Biologicals | NB100-2522 | 13 references | Polyclonal |
WB
ICC
IP
IHC |
|
Proteintech Group | 13572-1-AP | 43 references | Polyclonal |
WB
EL
IHC
|
|
Invitrogen Antibodies | PA5-17215 | 2 references | Polyclonal |
WB
ICC
IP
OA |
|
antibodies-online | ABIN250952 | 11 references | Polyclonal |
WB
ICC
IP
IHC |
|
LSBio | LS-C100492 | Polyclonal |
WB
IHC |
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Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider