Tissue expression
			
			Cell line expression
			
					
			Protein structure
		
	SIRT6
Sirtuin 6This gene encodes a member of the sirtuin family of NAD-dependent enzymes that are implicated in cellular stress resistance, genomic stability, aging and energy homeostasis. The encoded protein is localized to the nucleus, exhibits ADP-ribosyl transferase and histone deacetylase activities, and plays a role in DNA repair, maintenance of telomeric chromatin, inflammation, lipid and glucose metabolism. Alternative splicing results in multiple transcript variants encoding different isoforms.  [provided by RefSeq, Mar 2016]
	| Top validated antibodies | |||||
| Novus Biologicals |  NB100-2522 | 13 references | Polyclonal |  | |
| Proteintech Group |  13572-1-AP | 43 references | Polyclonal |  | |
| antibodies-online |  ABIN250952 | 11 references | Polyclonal |  | |
| Invitrogen Antibodies |  PA5-17215 | 2 references | Polyclonal |  | |
| LSBio |  LS-C100492 | Polyclonal |  | ||