Tissue expression
Cell line expression
Protein structure
SUV39H1
Suppressor of variegation 3-9 homolog 1KMT1A, SUV39H
This gene encodes an evolutionarily-conserved protein containing an N-terminal chromodomain and a C-terminal SET domain. The encoded protein is a histone methyltransferase that trimethylates lysine 9 of histone H3, which results in transcriptional gene silencing. Loss of function of this gene disrupts heterochromatin formation and may cause chromosome instability. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
Top validated antibodies |
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| GeneTex | 5 references | Polyclonal |
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| Proteintech Group | 15 references | Polyclonal |
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| Invitrogen Antibodies | 1 references | Polyclonal |
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| Novus Biologicals | 3 references | Polyclonal |
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| LSBio | Polyclonal |
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