Tissue expression
Cell line expression
Protein structure
PIM1
Pim-1 proto-oncogene, serine/threonine kinasePIM
The protein encoded by this gene belongs to the Ser/Thr protein kinase family, and PIM subfamily. This gene is expressed primarily in B-lymphoid and myeloid cell lines, and is overexpressed in hematopoietic malignancies and in prostate cancer. It plays a role in signal transduction in blood cells, contributing to both cell proliferation and survival, and thus provides a selective advantage in tumorigenesis. Both the human and orthologous mouse genes have been reported to encode two isoforms (with preferential cellular localization) resulting from the use of alternative in-frame translation initiation codons, the upstream non-AUG (CUG) and downstream AUG codons (PMIDs:16186805, 1825810). [provided by RefSeq, Aug 2011]
Top validated antibodies |
|||||
Invitrogen Antibodies | 710504 | 1 references | Polyclonal |
WB
ICC
IHC
OA |
|
antibodies-online | ABIN2842038 | 5 references | Polyclonal |
WB
IHC |
|
Abgent | AP7932a | 4 references | Polyclonal |
WB
IHC |
|
Boster Biological Technology | M01184 | 1 references | Monoclonal |
WB
ICC
IHC
|
|
Abnova Corporation | PAB2304 | 3 references | Polyclonal |
WB
IHC |
All Antibodies
Filters
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider