Tissue expression
Cell line expression
Protein structure
CPB2
Carboxypeptidase B2CPU, PCPB, TAFI
Carboxypeptidases are enzymes that hydrolyze C-terminal peptide bonds. The carboxypeptidase family includes metallo-, serine, and cysteine carboxypeptidases. According to their substrate specificity, these enzymes are referred to as carboxypeptidase A (cleaving aliphatic residues) or carboxypeptidase B (cleaving basic amino residues). The protein encoded by this gene is activated by trypsin and acts on carboxypeptidase B substrates. After thrombin activation, the mature protein downregulates fibrinolysis. Polymorphisms have been described for this gene and its promoter region. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013]
Top validated antibodies |
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Cusabio Biotech Co., Ltd | ![]() |
Polyclonal |
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LSBio | ![]() |
Polyclonal |
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Biorbyt | ![]() |
Polyclonal |
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Proteintech Group | ![]() |
2 references | Polyclonal |
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Invitrogen Antibodies | ![]() |
1 references | Monoclonal |
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