Tissue expression
Cell line expression
Protein structure

HDAC8

Histone deacetylase 8
HDACL1, KDAC8, MRXS6, RPD3, WTS 
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class I of the histone deacetylase family. It catalyzes the deacetylation of lysine residues in the histone N-terminal tails and represses transcription in large multiprotein complexes with transcriptional co-repressors. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]
More gene data

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793 antibodies from 44 providers.

Antibody properties

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AntibodyRefsTypeWBELICCIPIHCFC
Proteintech Group
1 antibody
Novus Biologicals
7 antibodies
GeneTex
6 antibodies
Invitrogen Antibodies
40 antibodies
Boster Biological Technology
6 antibodies
Biorbyt
106 antibodies
HUABIO Research
2 antibodies
antibodies-online
232 antibodies
BioLegend
3 antibodies
Abnova Corporation
11 antibodies
St John's Laboratory
5 antibodies
Affinity Biosciences
2 antibodies
Atlas Antibodies
1 antibody
OriGene
31 antibodies
Cusabio Biotech Co., Ltd
16 antibodies
NovoPro Bioscience Inc.
4 antibodies
Acris Antibodies GmbH
10 antibodies
FineTest Biotech
2 antibodies
Abgent
3 antibodies
Aviva Systems Biology
5 antibodies
NSJ Bioreagents
2 antibodies
Arigo
2 antibodies
R&D Systems
2 antibodies
Signalway Antibody LLC
1 antibody
Bioworld Technology, Inc
3 antibodies
ProSci
2 antibodies
Cell Signaling Technology, Inc
1 antibody
Abbkine Scientific Co.Ltd.
2 antibodies
Creative Diagnostics
7 antibodies
RabMAbs
3 antibodies
SignalChem
1 antibody
Abbexa
22 antibodies
MilliporeSigma / Merck KGaA
7 antibodies
MyBioSource
7 antibodies
Leading Biology
2 antibodies
RayBiotech, Inc.
2 antibodies
Abiocode, Inc.
1 antibody
United States Biological
76 antibodies
GenWay
4 antibodies
Creative Biolabs
15 antibodies
EMD Millipore
1 antibody
Rockland Immunochemicals, Inc.
2 antibodies