VIL1

This gene encodes a member of a family of calcium-regulated actin-binding proteins. This protein represents a dominant part of the brush border cytoskeleton which functions in the capping, severing, and bundling of actin filaments. Two mRNAs of 2.7 kb and 3.5 kb have been observed; they result from utilization of alternate poly-adenylation signals present in the terminal exon. [provided by RefSeq, Jul 2008]

Description

Villin 1

Tissue specificity

Tissue enriched (intestine)

Subcell location

Plasma membrane

Predicted location

Intracellular

Protein family

Cancer-related genes
Disease related genes
Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Plasma proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)

Chromosome

2:q35 (218419121 - 218453295)

Ensembl ID

ENSG00000127831  (ver. 103.38)

Orthologs

Mouse Vil1: ENSMUSG00000026175

UniProt

P09327

neXtProt

NX_P09327

Human splice variants
Mouse splice variants