TRIM32

The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic bodies. The protein has also been localized to the nucleus, where it interacts with the activation domain of the HIV-1 Tat protein. The Tat protein activates transcription of HIV-1 genes. [provided by RefSeq, Jul 2008]

Description

tripartite motif containing 32

Protein family

Disease related genes, Enzymes, Mapped to neXtProt, Mapped to UniProt SWISS-PROT, Potential drug targets, Predicted intracellular proteins, Protein evidence (Peptideatlas)

Chromosome

9:q33.1 (116687302 - 116701300)

Ensembl ID

ENSG00000119401  (ver. 99.38)

Orthologs

Mouse Trim32: ENSMUSG00000051675

UniProt

Q13049

neXtProt

NX_Q13049

Human splice variants
Mouse splice variants