GPI

gene product
AMF, NLK
This gene encodes a member of the glucose phosphate isomerase protein family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. In the cytoplasm, the gene product functions as a glycolytic enzyme (glucose-6-phosphate isomerase) that interconverts glucose-6-phophsate and fructose-6-phosphate. Extracellularly, the encoded protein (also referred to as neuroleukin) functions as a neurotrophic factor that promotes survival of skeletal motor neurons and sensory neurons, and as a lymphokine that induces immunoglobulin secretion. The encoded protein is also referred to as autocrine motility factor based on an additional function as a tumor-secreted cytokine and angiogenic factor. Defects in this gene are the cause of nonspherocytic hemolytic anemia and a severe enzyme deficiency can be associated with hydrops fetalis, immediate neonatal death and neurological impairment. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]
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585 antibodies from 36 providers.

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AntibodyRefsTypeWBELICCIPIHCFC
Atlas Antibodies
2 antibodies
Novus Biologicals
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antibodies-online
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OriGene
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Biorbyt
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Affinity Biosciences
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Bethyl Laboratories
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Abgent
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Bioworld Technology, Inc
1 antibody
Arigo
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Santa Cruz Biotechnology
1 antibody
Antibodies.com
2 antibodies
Sigma-Aldrich
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Proteintech Group
1 antibody
NSJ Bioreagents
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Everest Biotech
2 antibodies
Aviva Systems Biology
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ProSci
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MyBioSource
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Creative Biolabs
5 antibodies
Creative Diagnostics
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RayBiotech, Inc.
4 antibodies
RabMAbs
2 antibodies
Boster Biological Technology
2 antibodies
EMD Millipore
1 antibody
United States Biological
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Abbiotec
1 antibody
Abbexa
6 antibodies