Tissue expression
Cell line expression

CYP3A4

gene product
CYP3A3 
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases that catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by glucocorticoids and some pharmacological agents. This enzyme is involved in the metabolism of approximately half the drugs in use today, including acetaminophen, codeine, cyclosporin A, diazepam, erythromycin, and chloroquine. The enzyme also metabolizes some steroids and carcinogens. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Previously another CYP3A gene, CYP3A3, was thought to exist; however, it is now thought that this sequence represents a transcript variant of CYP3A4. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2020]
More gene data

Antibodies

 

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Supportive data in Antibodypedia
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643 antibodies from 39 providers.

Antibody properties

Applications

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AntibodyRefsTypeWBELICCIPIHCFC
antibodies-online
204 antibodies
Novus Biologicals
62 antibodies
Proteintech Group
3 antibodies
Invitrogen Antibodies
11 antibodies
OriGene
13 antibodies
GeneTex
8 antibodies
Acris Antibodies GmbH
7 antibodies
LifeSpan BioSciences, Inc.
72 antibodies
Biorbyt
55 antibodies
Abnova Corporation
7 antibodies
Cusabio Biotech Co., Ltd
11 antibodies
Affinity Biosciences
4 antibodies
NovoPro Bioscience Inc.
5 antibodies
Abgent
4 antibodies
Arigo
2 antibodies
Wuhan Fine Biotech Co., Ltd.
1 antibody
Boster Biological Technology
4 antibodies
St John's Laboratory
8 antibodies
Bioworld Technology, Inc
3 antibodies
ProSci
2 antibodies
HUABIO Research
1 antibody
NSJ Bioreagents
2 antibodies
Abbexa
20 antibodies
Abbkine Scientific Co.Ltd.
2 antibodies
Aviva Systems Biology
9 antibodies
RabMAbs
3 antibodies
MilliporeSigma / Merck KGaA
3 antibodies
MyBioSource
11 antibodies
Creative Biolabs
15 antibodies
R&D Systems
1 antibody
United States Biological
41 antibodies
Creative Diagnostics
9 antibodies
Leading Biology
4 antibodies
Cell Signaling Technology, Inc
1 antibody
Enzo Life Sciences
4 antibodies
EMD Millipore
3 antibodies
GenWay
2 antibodies
Everest Biotech
1 antibody