Tissue expression
Cell line expression
Protein structure

CYP3A4

Cytochrome P450 family 3 subfamily A member 4
CYP3A3 
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases that catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by glucocorticoids and some pharmacological agents. This enzyme is involved in the metabolism of approximately half the drugs in use today, including acetaminophen, codeine, cyclosporin A, diazepam, erythromycin, and chloroquine. The enzyme also metabolizes some steroids and carcinogens. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Previously another CYP3A gene, CYP3A3, was thought to exist; however, it is now thought that this sequence represents a transcript variant of CYP3A4. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2020]
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715 antibodies from 39 providers.

Antibody properties

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AntibodyRefsTypeWBELICCIPIHCFC
Invitrogen Antibodies
29 antibodies
antibodies-online
204 antibodies
Novus Biologicals
62 antibodies
Proteintech Group
3 antibodies
OriGene
13 antibodies
GeneTex
8 antibodies
Acris Antibodies GmbH
7 antibodies
Abnova Corporation
7 antibodies
Biorbyt
106 antibodies
Cusabio Biotech Co., Ltd
11 antibodies
Affinity Biosciences
4 antibodies
NovoPro Bioscience Inc.
5 antibodies
Abgent
4 antibodies
Arigo
2 antibodies
FineTest Biotech
1 antibody
NSJ Bioreagents
4 antibodies
St John's Laboratory
7 antibodies
Boster Biological Technology
4 antibodies
Bioworld Technology, Inc
3 antibodies
ProSci
2 antibodies
Everest Biotech
1 antibody
HUABIO Research
1 antibody
Abbexa
20 antibodies
Abbkine Scientific Co.Ltd.
2 antibodies
Aviva Systems Biology
9 antibodies
RabMAbs
3 antibodies
MilliporeSigma / Merck KGaA
3 antibodies
MyBioSource
11 antibodies
Creative Biolabs
16 antibodies
R&D Systems
1 antibody
United States Biological
41 antibodies
Creative Diagnostics
9 antibodies
Leading Biology
4 antibodies
Cell Signaling Technology, Inc
1 antibody
Enzo Life Sciences
4 antibodies
EMD Millipore
3 antibodies
GenWay
2 antibodies