CYP3A4

gene product
CYP3A3
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases that catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by glucocorticoids and some pharmacological agents. This enzyme is involved in the metabolism of approximately half the drugs in use today, including acetaminophen, codeine, cyclosporin A, diazepam and erythromycin. The enzyme also metabolizes some steroids and carcinogens. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Previously another CYP3A gene, CYP3A3, was thought to exist; however, it is now thought that this sequence represents a transcript variant of CYP3A4. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Feb 2011]
More gene data

Featured antibodies

Antibodies

 

Filters

Application

Antibodypedia Validation Initiative

Validation method

Reference

Provider

Host

Reactivity

Antibody type

Conjugate

Antibody

  or   Clear
Enhanced validation
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Validated within AVI
Eligible for validation within AVI
597 antibodies from 35 providers.

Antibody properties

General

Applications

or Cancel
AntibodyRefsTypeWBELICCIPIHCFC
antibodies-online
204 antibodies
Novus Biologicals
62 antibodies
GeneTex
8 antibodies
OriGene
9 antibodies
Acris Antibodies GmbH
7 antibodies
LifeSpan BioSciences, Inc.
71 antibodies
Invitrogen Antibodies
5 antibodies
Biorbyt
55 antibodies
Abnova Corporation
7 antibodies
Proteintech Group
1 antibody
Affinity Biosciences
4 antibodies
NovoPro Bioscience Inc.
5 antibodies
Abgent
4 antibodies
Arigo
2 antibodies
St John's Laboratory
8 antibodies
Boster Biological Technology
3 antibodies
Bioworld Technology, Inc
3 antibodies
ProSci
2 antibodies
NSJ Bioreagents
2 antibodies
Abbexa
7 antibodies
Abbkine Scientific Co.Ltd.
2 antibodies
Aviva Systems Biology
9 antibodies
Creative Biolabs
15 antibodies
RabMAbs
3 antibodies
MyBioSource
11 antibodies
R&D Systems
1 antibody
United States Biological
41 antibodies
Creative Diagnostics
9 antibodies
Cell Signaling Technology, Inc
1 antibody
Enzo Life Sciences
4 antibodies
EMD Millipore
3 antibodies
GenWay
2 antibodies
Sigma-Aldrich
2 antibodies
Everest Biotech
1 antibody