Tissue expression
Cell line expression

PML

gene product
MYL, RNF71, TRIM19 
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This phosphoprotein localizes to nuclear bodies where it functions as a transcription factor and tumor suppressor. Its expression is cell-cycle related and it regulates the p53 response to oncogenic signals. The gene is often involved in the translocation with the retinoic acid receptor alpha gene associated with acute promyelocytic leukemia (APL). Extensive alternative splicing of this gene results in several variations of the protein's central and C-terminal regions; all variants encode the same N-terminus. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
More gene data

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599 antibodies from 44 providers.

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AntibodyRefsTypeWBELICCIPIHCFC
Novus Biologicals
27 antibodies
Proteintech Group
1 antibody
antibodies-online
178 antibodies
Invitrogen Antibodies
22 antibodies
Biorbyt
23 antibodies
Santa Cruz Biotechnology
2 antibodies
Abnova Corporation
14 antibodies
NSJ Bioreagents
3 antibodies
Abgent
3 antibodies
LifeSpan BioSciences, Inc.
93 antibodies
Enzo Life Sciences
1 antibody
Aviva Systems Biology
5 antibodies
OriGene
19 antibodies
Acris Antibodies GmbH
17 antibodies
Cusabio Biotech Co., Ltd
2 antibodies
Affinity Biosciences
1 antibody
GeneTex
3 antibodies
Boster Biological Technology
5 antibodies
St John's Laboratory
5 antibodies
Bioworld Technology, Inc
2 antibodies
ProSci
2 antibodies
NovoPro Bioscience Inc.
4 antibodies
Bethyl Laboratories
3 antibodies
Atlas Antibodies
1 antibody
Wuhan Fine Biotech Co., Ltd.
1 antibody
Abbiotec
1 antibody
MilliporeSigma / Merck KGaA
7 antibodies
Cell Signaling Technology, Inc
2 antibodies
Abbkine Scientific Co.Ltd.
1 antibody
MyBioSource
8 antibodies
Arigo
2 antibodies
Abbexa
5 antibodies
Creative Biolabs
18 antibodies
RabMAbs
2 antibodies
Creative Diagnostics
6 antibodies
RayBiotech, Inc.
2 antibodies
United States Biological
69 antibodies
Spring Bioscience
4 antibodies
Abiocode, Inc.
2 antibodies
EMD Millipore
3 antibodies
Leading Biology
3 antibodies
Active Motif
1 antibody
Rockland Immunochemicals, Inc.
1 antibody