Tissue expression
Cell line expression
Protein structure
HIF3A
Hypoxia inducible factor 3 subunit alphabHLHe17, IPAS, MOP7, PASD7
The protein encoded by this gene is the alpha-3 subunit of one of several alpha/beta-subunit heterodimeric transcription factors that regulate many adaptive responses to low oxygen tension (hypoxia). The alpha-3 subunit lacks the transactivation domain found in factors containing either the alpha-1 or alpha-2 subunits. It is thought that factors containing the alpha-3 subunit are negative regulators of hypoxia-inducible gene expression. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2011]
Top validated antibodies |
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| Novus Biologicals | 5 references | Polyclonal |
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| LSBio | Monoclonal |
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| Proteintech Group | 5 references | Polyclonal |
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| antibodies-online | 6 references | Polyclonal |
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| GeneTex | Polyclonal |
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