PRDM1

This gene encodes a protein that acts as a repressor of beta-interferon gene expression. The protein binds specifically to the PRDI (positive regulatory domain I element) of the beta-IFN gene promoter. Transcription of this gene increases upon virus induction. Two alternatively spliced transcript variants that encode different isoforms have been reported. [provided by RefSeq, Jul 2008]

Description

PR/SET domain 1

Protein family

Cancer-related genes, Mapped to neXtProt, Mapped to UniProt SWISS-PROT, Predicted intracellular proteins, Protein evidence (Peptideatlas), Transcription factors

Chromosome

6:q21 (105993463 - 106109939)

Ensembl ID

ENSG00000057657  (ver. 99.38)

Orthologs

Mouse Prdm1: ENSMUSG00000038151

UniProt

O75626

neXtProt

NX_O75626

Human splice variants
Mouse splice variants