GREM1

gene product
CKTSF1B1, CRAC1, DAND2, DRM, gremlin, HMPS
This gene encodes a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted glycosylated protein encoded by this gene is likely due to its direct binding to BMP proteins. As an antagonist of BMP, this gene may play a role in regulating organogenesis, body patterning, and tissue differentiation. In mouse, this protein has been shown to relay the sonic hedgehog (SHH) signal from the polarizing region to the apical ectodermal ridge during limb bud outgrowth. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2010]
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402 antibodies from 30 providers.

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AntibodyRefsTypeAVIWBELICCIPIHCFC
Abnova Corporation
12 antibodies
antibodies-online
90 antibodies
Novus Biologicals
22 antibodies
Biorbyt
9 antibodies
R&D Systems
3 antibodies
Invitrogen Antibodies
4 antibodies
GeneTex
3 antibodies
LifeSpan BioSciences, Inc.
82 antibodies
NovoPro Bioscience Inc.
4 antibodies
Acris Antibodies GmbH
14 antibodies
OriGene
12 antibodies
Aviva Systems Biology
3 antibodies
Abgent
1 antibody
Arigo
1 antibody
ProSci
3 antibodies
Sino Biological Inc.
2 antibodies
Rockland Immunochemicals, Inc.
1 antibody
MyBioSource
14 antibodies
ReliaTech GmbH
4 antibodies
Atlas Antibodies
1 antibody
NSJ Bioreagents
1 antibody
Creative Diagnostics
6 antibodies
Boster Biological Technology
1 antibody
Cell Signaling Technology, Inc
1 antibody
United States Biological
80 antibodies
Creative Biolabs
10 antibodies
Sigma-Aldrich
3 antibodies
RayBiotech, Inc.
1 antibody
GenWay
2 antibodies