TPBG

This gene encodes a leucine-rich transmembrane glycoprotein that may be involved in cell adhesion. The encoded protein is an oncofetal antigen that is specific to trophoblast cells. In adults this protein is highly expressed in many tumor cells and is associated with poor clinical outcome in numerous cancers. Alternate splicing in the 5' UTR results in multiple transcript variants that encode the same protein. [provided by RefSeq, Oct 2009]

Description

trophoblast glycoprotein

Protein family

Mapped to UniProt SWISS-PROT, Predicted membrane proteins, Protein evidence (Ezkurdia et al 2014), Protein evidence (Kim et al 2014)

Chromosome

6:q14.1 (82363206 - 82370828)

Ensembl ID

ENSG00000146242  (ver. 84.38)

Orthologs

Mouse Tpbg: ENSMUSG00000035274

UniProt

Q13641

neXtProt

NX_Q13641

Human splice variants
Mouse splice variants