Explore
Validate
LearnTissue expression
Cell line expression
Protein structure
SIRT2
Sirtuin 2SIR2L
This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Several transcript variants are resulted from alternative splicing of this gene. [provided by RefSeq, Jul 2010]
Top validated antibodies |
|||||
| Invitrogen Antibodies |  PA3-200 |
6 references | Polyclonal |
WB
ICC
IHC
OA
|
|
| Atlas Antibodies | HPA011165 |
1 references | Polyclonal |
WB
ICC
IHC
|
|
| Novus Biologicals | H00022933-M01 |
1 references | Monoclonal |
WB
EL
ICC
BN
|
|
| Proteintech Group | 19655-1-AP |
Polyclonal |
WB
EL
ICC
IP
IHC
|
||
| NovoPro Bioscience Inc. | 115243 |
Polyclonal |
WB
EL
ICC
IP
IHC
|
||
All Antibodies
Filters
Enhanced validation Supportive data in Antibodypedia Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider