Tissue expression
Cell line expression
Protein structure
DLC1
DLC1 Rho GTPase activating proteinARHGAP7, DLC-1, HP, p122-RhoGAP, STARD12
This gene encodes a GTPase-activating protein (GAP) that is a member of the rhoGAP family of proteins which play a role in the regulation of small GTP-binding proteins. GAP family proteins participate in signaling pathways that regulate cell processes involved in cytoskeletal changes. This gene functions as a tumor suppressor gene in a number of common cancers, including prostate, lung, colorectal, and breast cancers. Multiple transcript variants due to alternative promoters and alternative splicing have been found for this gene. [provided by RefSeq, Apr 2010]
Top validated antibodies |
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| Proteintech Group | 1 references | Polyclonal |
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| LSBio | Polyclonal |
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| Invitrogen Antibodies | 1 references | Polyclonal |
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| Atlas Antibodies | 2 references | Polyclonal |
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| Novus Biologicals | 1 references | Polyclonal |
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