Tissue expression
Cell line expression
Protein structure

WRAP53

WD repeat containing antisense to TP53
FLJ10385, TCAB1, WDR79 
This gene encodes an essential component of the telomerase holoenzyme complex, a ribonucleoprotein complex required for telomere synthesis. This protein is enriched in Cajal bodies, nuclear sites of RNP processing that are important for telomerase function. It interacts with dyskerin, TERT and TERC, other components of active telomerase, and with small Cajal body RNAs (scaRNAs), which are involved in modifying splicing RNAs. This mRNA also functions as a p53 antisense transcript, that regulates endogenous p53 mRNA levels and further induction of p53 protein by targeting the 5' untranslated region of p53 mRNA. Alternatively spliced transcript variants which differ only in the 5' UTR have been found for this gene. [provided by RefSeq, Mar 2011]
More gene data

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85 antibodies from 22 providers.

Antibody properties

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AntibodyRefsTypeWBELICCIPIHCFC
Novus Biologicals
7 antibodies
Atlas Antibodies
3 antibodies
Proteintech Group
1 antibody
antibodies-online
19 antibodies
Abnova Corporation
4 antibodies
Invitrogen Antibodies
17 antibodies
FineTest Biotech
1 antibody
NovoPro Bioscience Inc.
1 antibody
LSBio
6 antibodies
Bethyl Laboratories
2 antibodies
Abgent
1 antibody
Cusabio Biotech Co., Ltd
1 antibody
Affinity Biosciences
1 antibody
Creative Diagnostics
4 antibodies
St John's Laboratory
2 antibodies
Bioss
3 antibodies
MyBioSource
2 antibodies
MilliporeSigma / Merck KGaA
2 antibodies
Creative Biolabs
5 antibodies
Leading Biology
1 antibody
United States Biological
1 antibody
Abbexa
1 antibody