Tissue expression
Cell line expression

TMPRSS2

gene product
PRSS10 
This gene encodes a protein that belongs to the serine protease family. The encoded protein contains a type II transmembrane domain, a receptor class A domain, a scavenger receptor cysteine-rich domain and a protease domain. Serine proteases are known to be involved in many physiological and pathological processes. This gene was demonstrated to be up-regulated by androgenic hormones in prostate cancer cells and down-regulated in androgen-independent prostate cancer tissue. The protease domain of this protein is thought to be cleaved and secreted into cell media after autocleavage. This protein also facilitates entry of viruses into host cells by proteolytically cleaving and activating viral envelope glycoproteins. Viruses found to use this protein for cell entry include Influenza virus and the human coronaviruses HCoV-229E, MERS-CoV, SARS-CoV and SARS-CoV-2 (COVID-19 virus). Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2020]
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318 antibodies from 35 providers.

Antibody properties

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AntibodyRefsTypeWBELICCIPIHCFC
Invitrogen Antibodies
16 antibodies
Proteintech Group
1 antibody
Atlas Antibodies
1 antibody
Biorbyt
19 antibodies
antibodies-online
87 antibodies
GeneTex
6 antibodies
Novus Biologicals
4 antibodies
Abgent
4 antibodies
LifeSpan BioSciences, Inc.
50 antibodies
St John's Laboratory
4 antibodies
Aviva Systems Biology
5 antibodies
Wuhan Fine Biotech Co., Ltd.
1 antibody
Abnova Corporation
4 antibodies
Boster Biological Technology
1 antibody
NovoPro Bioscience Inc.
2 antibodies
RabMAbs
4 antibodies
Affinity Biosciences
1 antibody
Antibodies.com
1 antibody
Bioworld Technology, Inc
1 antibody
Cusabio Biotech Co., Ltd
1 antibody
Acris Antibodies GmbH
5 antibodies
Everest Biotech
1 antibody
NSJ Bioreagents
1 antibody
OriGene
4 antibodies
MyBioSource
4 antibodies
ProSci
2 antibodies
Arigo
1 antibody
Abiocode, Inc.
3 antibodies
Abbexa
5 antibodies
Creative Diagnostics
3 antibodies
United States Biological
27 antibodies
MilliporeSigma / Merck KGaA
4 antibodies
Creative Biolabs
29 antibodies
Leading Biology
1 antibody