Explore
Validate
LearnTissue expression
Cell line expression
TRIOBP
gene productDFNB28, HRIHFB2122, KIAA1662, TAP68, Tara
This gene encodes a protein with an N-terminal pleckstrin homology domain and a C-terminal coiled-coil region. The protein interacts with trio, which is involved with neural tissue development and controlling actin cytoskeleton organization, cell motility and cell growth. The protein also associates with F-actin and stabilizes F-actin structures. Mutations in this gene have been associated with a form of autosomal recessive nonsyndromic deafness. Multiple alternatively spliced transcript variants that would encode different isoforms have been found for this gene, however some transcripts may be subject to nonsense-mediated decay (NMD). [provided by RefSeq, Nov 2008]
Featured antibodies
 GeneTex |
 GTX110158 |
0 references | Polyclonal |
WB
ICC
IHC
|
Antibodies
Filters
Enhanced validation Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider