EP300

gene product
KAT3B, p300
This gene encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. It functions as histone acetyltransferase that regulates transcription via chromatin remodeling and is important in the processes of cell proliferation and differentiation. It mediates cAMP-gene regulation by binding specifically to phosphorylated CREB protein. This gene has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF. Defects in this gene are a cause of Rubinstein-Taybi syndrome and may also play a role in epithelial cancer. [provided by RefSeq, Jul 2008]
More gene data

Antibodies

 

Filters

Application

Antibodypedia Validation Initiative

Validation method

Reference

Provider

Host

Reactivity

Antibody type

Conjugate

  or   Clear
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider
Validated within AVI
Eligible for validation within AVI
955 antibodies from 36 providers.

Antibody properties

General

Applications

or Cancel
AntibodyRefsTypeWBELICCIPIHCFC
Novus Biologicals
50 antibodies
antibodies-online
366 antibodies
GeneTex
8 antibodies
Invitrogen Antibodies
10 antibodies
Bethyl Laboratories
3 antibodies
Abnova Corporation
13 antibodies
Acris Antibodies GmbH
17 antibodies
OriGene
18 antibodies
R&D Systems
2 antibodies
LifeSpan BioSciences, Inc.
167 antibodies
NovoPro Bioscience Inc.
7 antibodies
Biorbyt
60 antibodies
Cell Signaling Technology, Inc
3 antibodies
Abgent
8 antibodies
Affinity Biosciences
5 antibodies
Aviva Systems Biology
8 antibodies
St John's Laboratory
10 antibodies
Atlas Antibodies
2 antibodies
NSJ Bioreagents
1 antibody
Bioworld Technology, Inc
3 antibodies
Abbkine Scientific Co.Ltd.
7 antibodies
Creative Diagnostics
7 antibodies
Boster Biological Technology
1 antibody
ProSci
2 antibodies
RabMAbs
2 antibodies
MyBioSource
15 antibodies
RayBiotech, Inc.
4 antibodies
Creative Biolabs
2 antibodies
GenWay
3 antibodies
United States Biological
105 antibodies