KCNJ5

Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, is controlled by G-proteins. It may associate with two other G-protein-activated potassium channels to form a heteromultimeric pore-forming complex. [provided by RefSeq, Jul 2008]

Description

potassium channel, inwardly rectifying subfamily J, member 5

Protein family

Cancer-related genes, Disease related genes, Mapped to UniProt SWISS-PROT, Potential drug targets, Predicted membrane proteins, Protein evidence (Kim et al 2014), Transporters, Voltage-gated ion channels

Chromosome

11:q24.3 (128891356 - 128921035)

Ensembl ID

ENSG00000120457  (ver. 84.38)

Orthologs

Mouse Kcnj5: ENSMUSG00000032034

UniProt

P48544

neXtProt

NX_P48544

Human splice variants
Mouse splice variants