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MTHFD2
Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolaseThis gene encodes a nuclear-encoded mitochondrial bifunctional enzyme with methylenetetrahydrofolate dehydrogenase and methenyltetrahydrofolate cyclohydrolase activities. The enzyme functions as a homodimer and is unique in its absolute requirement for magnesium and inorganic phosphate. Formation of the enzyme-magnesium complex allows binding of NAD. Alternative splicing results in two different transcripts, one protein-coding and the other not protein-coding. This gene has a pseudogene on chromosome 7. [provided by RefSeq, Mar 2009]
Top validated antibodies |
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| Invitrogen Antibodies |  PA5-28169 |
2 references | Polyclonal |
WB
ICC
IP
IHC
OA
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| Proteintech Group | 12270-1-AP |
41 references | Polyclonal |
WB
EL
IP
IHC
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| antibodies-online | ABIN443140 |
1 references | Polyclonal |
WB
ICC
IP
IHC
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| Novus Biologicals | NBP1-33200 |
1 references | Polyclonal |
WB
ICC
IP
IHC
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| GeneTex | GTX104990 |
Polyclonal |
WB
ICC
IP
IHC
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