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F11R
F11 receptorCD321, JAM-1, JAM-A, JAM1, JAMA, JCAM, PAM-1
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is an important regulator of tight junction assembly in epithelia. In addition, the encoded protein can act as (1) a receptor for reovirus, (2) a ligand for the integrin LFA1, involved in leukocyte transmigration, and (3) a platelet receptor. Multiple 5' alternatively spliced variants, encoding the same protein, have been identified but their biological validity has not been established. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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| Novus Biologicals |  H00050848-M01 |
8 references | Monoclonal |
WB
EL
ICC
IHC
PLA
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| Invitrogen Antibodies | 36-1700 |
77 references | Polyclonal |
WB
EL
IP
IHC
OA
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| Abnova Corporation | H00050848-M01 |
3 references | Monoclonal |
WB
EL
IHC
PLA
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| OriGene | SM2040PS |
Monoclonal |
WB
EL
ICC
IP
IHC
FC
FA
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| NSJ Bioreagents | RQ7077 |
Polyclonal |
WB
EL
ICC
IHC
FC
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