TYMS

gene product
HsT422, TMS, TS, Tsase
Thymidylate synthase catalyzes the methylation of deoxyuridylate to deoxythymidylate using 5,10-methylenetetrahydrofolate (methylene-THF) as a cofactor. This function maintains the dTMP (thymidine-5-prime monophosphate) pool critical for DNA replication and repair. The enzyme has been of interest as a target for cancer chemotherapeutic agents. It is considered to be the primary site of action for 5-fluorouracil, 5-fluoro-2-prime-deoxyuridine, and some folate analogs. Expression of this gene and that of a naturally occuring antisense transcript rTSalpha (GeneID:55556) vary inversely when cell-growth progresses from late-log to plateau phase. [provided by RefSeq, Jul 2008]
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1040 antibodies from 34 providers.

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AntibodyRefsTypeWBELICCIPIHCFC
antibodies-online
401 antibodies
Invitrogen Antibodies
8 antibodies
Novus Biologicals
74 antibodies
GeneTex
10 antibodies
Proteintech Group
1 antibody
Biorbyt
27 antibodies
Abgent
8 antibodies
Abnova Corporation
15 antibodies
Arigo
7 antibodies
Boster Biological Technology
5 antibodies
NovoPro Bioscience Inc.
1 antibody
OriGene
204 antibodies
Cell Signaling Technology, Inc
4 antibodies
St John's Laboratory
2 antibodies
Acris Antibodies GmbH
36 antibodies