Tissue expression
Cell line expression
Protein structure

CD59

CD59 molecule (CD59 blood group)
16.3A5, EJ16, EJ30, EL32, G344, MIC11, MIN1, MIN2, MIN3, MSK21, p18-20 
This gene encodes a cell surface glycoprotein that regulates complement-mediated cell lysis, and it is involved in lymphocyte signal transduction. This protein is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 and/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation. This protein also plays a role in signal transduction pathways in the activation of T cells. Mutations in this gene cause CD59 deficiency, a disease resulting in hemolytic anemia and thrombosis, and which causes cerebral infarction. Multiple alternatively spliced transcript variants, which encode the same protein, have been identified for this gene. [provided by RefSeq, Jul 2008]
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1983 antibodies from 44 providers.

Antibody properties

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AntibodyRefsTypeWBELICCIPIHCFC
GeneTex
26 antibodies
antibodies-online
703 antibodies
Proteintech Group
1 antibody
Invitrogen Antibodies
96 antibodies
Novus Biologicals
299 antibodies
OriGene
29 antibodies
NSJ Bioreagents
12 antibodies
NovoPro Bioscience Inc.
9 antibodies
Affinity Biosciences
3 antibodies
FineTest Biotech
1 antibody
Boster Biological Technology
12 antibodies
R&D Systems
12 antibodies
Antibodies.com
7 antibodies
Cusabio Biotech Co., Ltd
13 antibodies
Atlas Antibodies
1 antibody
HUABIO Research
1 antibody
St John's Laboratory
8 antibodies
Abnova Corporation
34 antibodies
Aviva Systems Biology
19 antibodies
Acris Antibodies GmbH
31 antibodies
Arigo
7 antibodies
Abbkine Scientific Co.Ltd.
1 antibody
Bioworld Technology, Inc
1 antibody
ProSci
9 antibodies
Creative Biolabs
147 antibodies
RabMAbs
3 antibodies
GenWay
21 antibodies
Abbexa
36 antibodies
International Blood Group Reference Laboratory
1 antibody
BioLegend
8 antibodies
Creative Diagnostics
7 antibodies
RayBiotech, Inc.
6 antibodies
Leading Biology
21 antibodies
Miltenyi Biotec
7 antibodies
Absolute Antibody
10 antibodies
United States Biological
30 antibodies
Abgent
8 antibodies
Cell Signaling Technology, Inc
1 antibody
EMD Millipore
2 antibodies
MilliporeSigma / Merck KGaA
5 antibodies
eBioscience, An Affymetrix Company
13 antibodies
Rockland Immunochemicals, Inc.
1 antibody