CD59

gene product
16.3A5, EJ16, EJ30, EL32, G344, MIC11, MIN1, MIN2, MIN3, MSK21, p18-20
This gene encodes a cell surface glycoprotein that regulates complement-mediated cell lysis, and it is involved in lymphocyte signal transduction. This protein is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 and/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation. This protein also plays a role in signal transduction pathways in the activation of T cells. Mutations in this gene cause CD59 deficiency, a disease resulting in hemolytic anemia and thrombosis, and which causes cerebral infarction. Multiple alternatively spliced transcript variants, which encode the same protein, have been identified for this gene. [provided by RefSeq, Jul 2008]
More gene data

Featured antibodies

Antibodies

 

Filters

Application

Antibodypedia Validation Initiative

Validation method

Reference

Provider

Host

Reactivity

Antibody type

Conjugate

Antibody

  or   Clear
Enhanced validation
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Validated within AVI
Eligible for validation within AVI
1948 antibodies from 43 providers.

Antibody properties

General

Applications

or Cancel
Antibody
GeneTex
26 antibodies
antibodies-online
703 antibodies
Proteintech Group
1 antibody
Novus Biologicals
299 antibodies
OriGene
29 antibodies
Biorbyt
89 antibodies
Invitrogen Antibodies
50 antibodies
NovoPro Bioscience Inc.
9 antibodies
LifeSpan BioSciences, Inc.
302 antibodies
Affinity Biosciences
3 antibodies
Boster Biological Technology
12 antibodies
NSJ Bioreagents
9 antibodies
R&D Systems
4 antibodies
Antibodies.com
7 antibodies
Cusabio Biotech Co., Ltd
13 antibodies
Atlas Antibodies
1 antibody
HUABIO Research
1 antibody
Abnova Corporation
34 antibodies
Aviva Systems Biology
19 antibodies
Acris Antibodies GmbH
31 antibodies
Arigo
7 antibodies
Abbkine Scientific Co.Ltd.
1 antibody
Bioworld Technology, Inc
1 antibody
ProSci
9 antibodies
St John's Laboratory
3 antibodies
Creative Biolabs
96 antibodies
RabMAbs
3 antibodies
GenWay
21 antibodies
Abbexa
36 antibodies
BioLegend
8 antibodies
Creative Diagnostics
7 antibodies
RayBiotech, Inc.
6 antibodies
Leading Biology
21 antibodies
Miltenyi Biotec
7 antibodies
United States Biological
30 antibodies
Abgent
8 antibodies
Cell Signaling Technology, Inc
1 antibody
EMD Millipore
2 antibodies
MilliporeSigma / Merck KGaA
5 antibodies
Rockland Immunochemicals, Inc.
1 antibody
eBioscience, An Affymetrix Company
13 antibodies
Absolute Antibody
4 antibodies