Tissue expression
Cell line expression
Protein structure
PPARG
Peroxisome proliferator activated receptor gammaNR1C3, PPARG1, PPARG2, PPARgamma
This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) subfamily of nuclear receptors. PPARs form heterodimers with retinoid X receptors (RXRs) and these heterodimers regulate transcription of various genes. Three subtypes of PPARs are known: PPAR-alpha, PPAR-delta, and PPAR-gamma. The protein encoded by this gene is PPAR-gamma and is a regulator of adipocyte differentiation. Additionally, PPAR-gamma has been implicated in the pathology of numerous diseases including obesity, diabetes, atherosclerosis and cancer. Alternatively spliced transcript variants that encode different isoforms have been described. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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| Proteintech Group | 431 references | Polyclonal |
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| Invitrogen Antibodies | Polyclonal |
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| Abnova Corporation | 3 references | Monoclonal |
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| R&D Systems | 3 references | Monoclonal |
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| Novus Biologicals | 3 references | Monoclonal |
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