Tissue expression
Cell line expression
Protein structure
MYL12A
Myosin light chain 12AMLCB, MRCL3, MRLC3, MYL2B
This gene encodes a nonsarcomeric myosin regulatory light chain. This protein is activated by phosphorylation and regulates smooth muscle and non-muscle cell contraction. This protein may also be involved in DNA damage repair by sequestering the transcriptional regulator apoptosis-antagonizing transcription factor (AATF)/Che-1 which functions as a repressor of p53-driven apoptosis. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 8. [provided by RefSeq, Dec 2014]
Top validated antibodies |
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| GeneTex | 5 references | Polyclonal |
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| Proteintech Group | 4 references | Polyclonal |
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| Acris Antibodies GmbH | 4 references | Polyclonal |
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| LSBio | Polyclonal |
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| Novus Biologicals | Polyclonal |
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