MORC4

In human, the four current members of the microrchidia (morc) gene family share an N-terminal ATPase-like ATP-binding region and a CW four-cysteine zinc-finger motif. The protein encoded by this gene also has a nuclear matrix binding domain and a two-stranded coiled-coil motif near its C-terminus. This gene is widely expressed at low levels in normal tissues and has elevated expression in placenta and testis. Alternative splicing results in multiple transcript variants encoding distinct proteins. [provided by RefSeq, Jan 2010]

Description

MORC family CW-type zinc finger 4

Tissue specificity

Tissue enhanced (placenta)

Subcell location

Nucleoplasm

Predicted location

Intracellular

Protein family

Cancer-related genes
Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)

Chromosome

X (106813871 - 107000212)

Ensembl ID

ENSG00000133131  (ver. 103.38)

Orthologs

Mouse Morc4: ENSMUSG00000031434

UniProt

Q8TE76

neXtProt

NX_Q8TE76

Human splice variants
Mouse splice variants

Protein structure