MECP2

gene product
MRX16, MRX79, RTT
DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD). Each of these proteins, with the exception of MBD3, is capable of binding specifically to methylated DNA. MECP2, MBD1 and MBD2 can also repress transcription from methylated gene promoters. In contrast to other MBD family members, MECP2 is X-linked and subject to X inactivation. MECP2 is dispensible in stem cells, but is essential for embryonic development. MECP2 gene mutations are the cause of most cases of Rett syndrome, a progressive neurologic developmental disorder and one of the most common causes of cognitive disability in females. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Oct 2015]
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838 antibodies from 46 providers.

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Antibody
Proteintech Group
1 antibody
antibodies-online
267 antibodies
Novus Biologicals
13 antibodies
GeneTex
8 antibodies
Invitrogen Antibodies
14 antibodies
Cell Signaling Technology, Inc
2 antibodies
NovoPro Bioscience Inc.
10 antibodies
Atlas Antibodies
2 antibodies
OriGene
20 antibodies
Abnova Corporation
12 antibodies
LifeSpan BioSciences, Inc.
162 antibodies
Biorbyt
33 antibodies
Acris Antibodies GmbH
13 antibodies
NSJ Bioreagents
6 antibodies
Bioworld Technology, Inc
1 antibody
St John's Laboratory
7 antibodies
PhosphoSolutions
3 antibodies
Antibodies.com
2 antibodies
Aviva Systems Biology
11 antibodies
Rockland Immunochemicals, Inc.
5 antibodies
Affinity Biosciences
3 antibodies
Creative Diagnostics
7 antibodies
FabGennix
6 antibodies
Boster Biological Technology
4 antibodies
Creative Biolabs
12 antibodies
Arigo
2 antibodies
Abbexa
13 antibodies
Abgent
10 antibodies
ProSci
5 antibodies
Antibodies Incorporated / NeuroMab
2 antibodies
MyBioSource
13 antibodies
Leading Biology
16 antibodies
Active Motif
3 antibodies
United States Biological
107 antibodies
BioLegend
6 antibodies
EMD Millipore
5 antibodies
RabMAbs
2 antibodies
RayBiotech, Inc.
2 antibodies
Abbiotec
1 antibody
Abbkine Scientific Co.Ltd.
1 antibody
Abiocode, Inc.
1 antibody
Sigma-Aldrich
9 antibodies
UC Davis/NIH NeuroMab Facility
2 antibodies
BioLegend (formerly Covance Antibody Products)
1 antibody
GenWay
1 antibody