EPO

gene product
EP
This gene encodes a secreted, glycosylated cytokine composed of four alpha helical bundles. The encoded protein is mainly synthesized in the kidney, secreted into the blood plasma, and binds to the erythropoietin receptor to promote red blood cell production, or erythropoiesis, in the bone marrow. Expression of this gene is upregulated under hypoxic conditions, in turn leading to increased erythropoiesis and enhanced oxygen-carrying capacity of the blood. Expression of this gene has also been observed in brain and in the eye, and elevated expression levels have been observed in diabetic retinopathy and ocular hypertension. Recombinant forms of the encoded protein exhibit neuroprotective activity against a variety of potential brain injuries, as well as antiapoptotic functions in several tissue types, and have been used in the treatment of anemia and to enhance the efficacy of cancer therapies. [provided by RefSeq, Aug 2017]
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Novus Biologicals
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R&D Systems
13 antibodies
antibodies-online
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GeneTex
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Invitrogen Antibodies
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OriGene
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NSJ Bioreagents
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Proteintech Group
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Boster Biological Technology
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LifeSpan BioSciences, Inc.
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Biorbyt
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Bioworld Technology, Inc
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PeproTech Inc.
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Affinity Biosciences
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Creative Diagnostics
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Arigo
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Aviva Systems Biology
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Abgent
5 antibodies
MyBioSource
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ABEOMICS Inc.
2 antibodies
BioLegend
2 antibodies
GenWay
5 antibodies
Abiocode, Inc.
3 antibodies
United States Biological
97 antibodies
Sigma-Aldrich
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ProSci
4 antibodies
EMD Millipore
2 antibodies
Abbexa
6 antibodies
Leading Biology
6 antibodies
Abbiotec
1 antibody
Sino Biological Inc.
1 antibody