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Protein structure
HNF1A
HNF1 homeobox AHNF1, LFB1, MODY3, TCF1
The protein encoded by this gene is a transcription factor required for the expression of several liver-specific genes. The encoded protein functions as a homodimer and binds to the inverted palindrome 5'-GTTAATNATTAAC-3'. Defects in this gene are a cause of maturity onset diabetes of the young type 3 (MODY3) and also can result in the appearance of hepatic adenomas. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2015]
Top validated antibodies |
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| GeneTex |  GTX113850 |
4 references | Polyclonal |
WB
ICC
IP
IHC
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| Novus Biologicals | NBP1-33596 |
4 references | Polyclonal |
WB
ICC
IP
IHC
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| antibodies-online | ABIN443456 |
2 references | Polyclonal |
WB
ICC
IP
IHC
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| Proteintech Group | 22426-1-AP |
11 references | Polyclonal |
WB
EL
IP
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| LSBio | LS-C832598 |
Polyclonal |
WB
EL
IHC
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