PRKCI

gene product
DXS1179E, PKCI
This gene encodes a member of the protein kinase C (PKC) family of serine/threonine protein kinases. The PKC family comprises at least eight members, which are differentially expressed and are involved in a wide variety of cellular processes. This protein kinase is calcium-independent and phospholipid-dependent. It is not activated by phorbolesters or diacylglycerol. This kinase can be recruited to vesicle tubular clusters (VTCs) by direct interaction with the small GTPase RAB2, where this kinase phosphorylates glyceraldehyde-3-phosphate dehydrogenase (GAPD/GAPDH) and plays a role in microtubule dynamics in the early secretory pathway. This kinase is found to be necessary for BCL-ABL-mediated resistance to drug-induced apoptosis and therefore protects leukemia cells against drug-induced apoptosis. There is a single exon pseudogene mapped on chromosome X. [provided by RefSeq, Jul 2008]
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Novus Biologicals
6 antibodies
GeneTex
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antibodies-online
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Abnova Corporation
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Proteintech Group
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Biorbyt
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Atlas Antibodies
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LifeSpan BioSciences, Inc.
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Invitrogen Antibodies
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Abgent
1 antibody
Arigo
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St John's Laboratory
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Abbkine Scientific Co.Ltd.
1 antibody
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1 antibody
Boster Biological Technology
1 antibody
Cell Signaling Technology, Inc
1 antibody
ProSci
1 antibody
RabMAbs
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Creative Diagnostics
4 antibodies
Aviva Systems Biology
2 antibodies
OriGene
1 antibody
United States Biological
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MyBioSource
5 antibodies
Creative Biolabs
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Sigma-Aldrich
4 antibodies
RayBiotech, Inc.
1 antibody
EMD Millipore
1 antibody
GenWay
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