Explore
Validate
LearnTissue expression
Cell line expression
SERPINA1
gene productA1A, A1AT, AAT, alpha-1-antitrypsin, alpha1AT, PI, PI1
The protein encoded by this gene is a serine protease inhibitor belonging to the serpin superfamily whose targets include elastase, plasmin, thrombin, trypsin, chymotrypsin, and plasminogen activator. This protein is produced in the liver, the bone marrow, by lymphocytic and monocytic cells in lymphoid tissue, and by the Paneth cells of the gut. Defects in this gene are associated with chronic obstructive pulmonary disease, emphysema, and chronic liver disease. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Aug 2020]
Featured antibodies
 GeneTex |
 GTX83666 |
0 references | Monoclonal |
WB
IP
IHC
FC
|
Antibodies
Filters
Enhanced validation Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider