Explore
Validate
LearnTissue expression
Cell line expression
Protein structure
SERPINA1
Serpin family A member 1A1A, A1AT, AAT, alpha-1-antitrypsin, alpha1AT, PI, PI1
The protein encoded by this gene is a serine protease inhibitor belonging to the serpin superfamily whose targets include elastase, plasmin, thrombin, trypsin, chymotrypsin, and plasminogen activator. This protein is produced in the liver, the bone marrow, by lymphocytic and monocytic cells in lymphoid tissue, and by the Paneth cells of the gut. Defects in this gene are associated with chronic obstructive pulmonary disease, emphysema, and chronic liver disease. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Aug 2020]
Top validated antibodies |
|||||
| Proteintech Group |  66135-1-Ig |
7 references | Monoclonal |
WB
EL
ICC
IP
IHC
FC
|
|
| Invitrogen Antibodies | PA5-16661 |
2 references | Polyclonal |
WB
ICC
IHC
FC
OA
|
|
| LSBio | LS-B10259 |
Monoclonal |
WB
IP
IHC
|
||
| antibodies-online | ABIN4352841 |
Monoclonal |
WB
EL
ICC
IHC
FC
|
||
| Novus Biologicals | NBP2-52557 |
Monoclonal |
WB
EL
ICC
IHC
FC
|
||
All Antibodies
Filters
Enhanced validation Supportive data in Antibodypedia Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider