LONP1

gene product
hLON, LonHS, PIM1, PRSS15
This gene encodes a mitochondrial matrix protein that belongs to the Lon family of ATP-dependent proteases. This protein mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides in the mitochondrial matrix. It may also have a chaperone function in the assembly of inner membrane protein complexes, and participate in the regulation of mitochondrial gene expression and maintenance of the integrity of the mitochondrial genome. Decreased expression of this gene has been noted in a patient with hereditary spastic paraplegia (PMID:18378094). Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Feb 2013]
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Antibodies

 

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Antibodypedia Validation Initiative

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245 antibodies from 24 providers.

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AntibodyRefsTypeWBELICCIPIHCFC
Novus Biologicals
20 antibodies
Proteintech Group
2 antibodies
Atlas Antibodies
1 antibody
NovoPro Bioscience Inc.
2 antibodies
Biorbyt
12 antibodies
antibodies-online
98 antibodies
Invitrogen Antibodies
3 antibodies
Abnova Corporation
4 antibodies
GeneTex
1 antibody
OriGene
1 antibody
LifeSpan BioSciences, Inc.
47 antibodies
Affinity Biosciences
1 antibody
Bethyl Laboratories
1 antibody
United States Biological
26 antibodies
MyBioSource
3 antibodies
Abgent
1 antibody
Aviva Systems Biology
1 antibody
Cell Signaling Technology, Inc
2 antibodies
St John's Laboratory
1 antibody
Creative Biolabs
1 antibody
Sigma-Aldrich
1 antibody
Abbexa
3 antibodies
ProSci
1 antibody