Tissue expression
Cell line expression
Protein structure
LONP1
Lon peptidase 1, mitochondrialhLON, LonHS, PIM1, PRSS15
This gene encodes a mitochondrial matrix protein that belongs to the Lon family of ATP-dependent proteases. This protein mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides in the mitochondrial matrix. It may also have a chaperone function in the assembly of inner membrane protein complexes, and participate in the regulation of mitochondrial gene expression and maintenance of the integrity of the mitochondrial genome. Decreased expression of this gene has been noted in a patient with hereditary spastic paraplegia (PMID:18378094). Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Feb 2013]
Top validated antibodies |
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Proteintech Group | 15440-1-AP | 85 references | Polyclonal |
WB
EL
ICC
IP
IHC
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Invitrogen Antibodies | 15440-1-AP | Polyclonal |
WB
ICC
IP
IHC
OA
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Novus Biologicals | NBP1-81734 | 9 references | Polyclonal |
WB
ICC
IHC
|
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Boster Biological Technology | A03808-2 | Polyclonal |
WB
EL
ICC
IHC
FC
|
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Atlas Antibodies | HPA002192 | 1 references | Polyclonal |
WB
ICC
IHC
|
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Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider