SMAD7

gene product
MADH7, MADH8
The protein encoded by this gene is a nuclear protein that binds the E3 ubiquitin ligase SMURF2. Upon binding, this complex translocates to the cytoplasm, where it interacts with TGF-beta receptor type-1 (TGFBR1), leading to the degradation of both the encoded protein and TGFBR1. Expression of this gene is induced by TGFBR1. Variations in this gene are a cause of susceptibility to colorectal cancer type 3 (CRCS3). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010]
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Invitrogen Antibodies
7 antibodies
Proteintech Group
2 antibodies
Novus Biologicals
33 antibodies
R&D Systems
1 antibody
antibodies-online
104 antibodies
OriGene
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NovoPro Bioscience Inc.
6 antibodies
Biorbyt
35 antibodies
Abgent
5 antibodies
Abnova Corporation
15 antibodies
Atlas Antibodies
1 antibody
Bioss
1 antibody
NSJ Bioreagents
1 antibody
LifeSpan BioSciences, Inc.
38 antibodies
GeneTex
8 antibodies
Acris Antibodies GmbH
4 antibodies
Arigo
4 antibodies
Aviva Systems Biology
3 antibodies
Boster Biological Technology
1 antibody
ProSci
4 antibodies
RabMAbs
3 antibodies
Abbkine Scientific Co.Ltd.
1 antibody
Affinity Biosciences
1 antibody
Creative Biolabs
40 antibodies
MyBioSource
7 antibodies
Abbiotec
1 antibody
Bioworld Technology, Inc
1 antibody
Rockland Immunochemicals, Inc.
1 antibody
United States Biological
162 antibodies
St John's Laboratory
3 antibodies
Creative Diagnostics
3 antibodies
Leading Biology
5 antibodies
RayBiotech, Inc.
3 antibodies
Sigma-Aldrich
3 antibodies
EMD Millipore
1 antibody
GenWay
1 antibody