ACTN4

gene product
FSGS1
Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, alpha actinin isoform which is concentrated in the cytoplasm, and thought to be involved in metastatic processes. Mutations in this gene have been associated with focal and segmental glomerulosclerosis. [provided by RefSeq, Jul 2008]
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411 antibodies from 37 providers.

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Novus Biologicals
11 antibodies
antibodies-online
117 antibodies
GeneTex
5 antibodies
Abnova Corporation
16 antibodies
Proteintech Group
1 antibody
Atlas Antibodies
1 antibody
NovoPro Bioscience Inc.
5 antibodies
OriGene
9 antibodies
Acris Antibodies GmbH
6 antibodies
Enzo Life Sciences
1 antibody
LifeSpan BioSciences, Inc.
54 antibodies
Boster Biological Technology
3 antibodies
Biorbyt
20 antibodies
Aviva Systems Biology
6 antibodies
Abgent
4 antibodies
Invitrogen Antibodies
5 antibodies
Signalway Antibody LLC
1 antibody
FabGennix
6 antibodies
Affinity Biosciences
1 antibody
St John's Laboratory
1 antibody
NSJ Bioreagents
3 antibodies
ProSci
6 antibodies
RabMAbs
7 antibodies
Bethyl Laboratories
1 antibody
Cell Signaling Technology, Inc
1 antibody
MyBioSource
11 antibodies
Creative Biolabs
42 antibodies
Creative Diagnostics
10 antibodies
RayBiotech, Inc.
2 antibodies
Arigo
1 antibody
United States Biological
30 antibodies
Abiocode, Inc.
3 antibodies
Sigma-Aldrich
4 antibodies
EMD Millipore
2 antibodies
Abbiotec
1 antibody
GenWay
2 antibodies