Tissue expression
Cell line expression
Protein structure
ABCB11
ATP binding cassette subfamily B member 11ABC16, BSEP, PFIC-2, PFIC2, PGY4, SPGP
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is the major canalicular bile salt export pump in man. Mutations in this gene cause a form of progressive familial intrahepatic cholestases which are a group of inherited disorders with severe cholestatic liver disease from early infancy. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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Invitrogen Antibodies | PA5-78690 | 2 references | Polyclonal |
WB
IHC
FC
OA |
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Boster Biological Technology | PB9414 | 2 references | Polyclonal |
WB
ICC
IHC
FC |
|
NSJ Bioreagents | R31844 | 3 references | Polyclonal |
WB
IHC
FC
|
|
antibodies-online | ABIN2840586 | 3 references | Polyclonal |
WB
IHC |
|
Abgent | AP6110A | 2 references | Polyclonal |
WB
IHC |
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Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider