Tissue expression
Cell line expression
Protein structure
ITGA2
Integrin subunit alpha 2CD49B
This gene encodes the alpha subunit of a transmembrane receptor for collagens and related proteins. The encoded protein forms a heterodimer with a beta subunit and mediates the adhesion of platelets and other cell types to the extracellular matrix. Loss of the encoded protein is associated with bleeding disorder platelet-type 9. Antibodies against this protein are found in several immune disorders, including neonatal alloimmune thrombocytopenia. This gene is located adjacent to a related alpha subunit gene. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]
Top validated antibodies |
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| GeneTex | Monoclonal |
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| Antibodies.com | Monoclonal |
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| Novus Biologicals | Monoclonal |
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| R&D Systems | 9 references | Monoclonal |
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| Boster Biological Technology | Polyclonal |
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