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Protein structure
LMAN1
Lectin, mannose binding 1ERGIC-53, ERGIC53, F5F8D, FMFD1, gp58, MCFD1, MR60
The protein encoded by this gene is a membrane mannose-specific lectin that cycles between the endoplasmic reticulum, endoplasmic reticulum-Golgi intermediate compartment, and cis-Golgi, functioning as a cargo receptor for glycoprotein transport. The protein has an N-terminal signal sequence, a calcium-dependent and pH-sensitive carbohydrate recognition domain, a stalk region that functions in oligomerization, a transmembrane domain, and a short cytoplasmic domain required for organelle targeting. Allelic variants of this gene are associated with the autosomal recessive disorder combined factor V-factor VIII deficiency. [provided by RefSeq, Jul 2015]
Top validated antibodies |
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| Proteintech Group |  13364-1-AP |
23 references | Polyclonal |
WB
EL
ICC
IP
IHC
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| Invitrogen Antibodies | MA5-25345 |
1 references | Monoclonal |
WB
ICC
IHC
FC
OA
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| Novus Biologicals | NBP2-03381 |
2 references | Monoclonal |
WB
ICC
IHC
FC
|
|
| LSBio | LS-C337181 |
Monoclonal |
WB
ICC
IHC
|
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| NSJ Bioreagents | RQ4585 |
Polyclonal |
WB
EL
ICC
IHC
FC
|
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