Explore
Validate
LearnTissue expression
Cell line expression
Protein structure
NUDT5
Nudix hydrolase 5hYSAH1, YSA1H
This gene belongs to the Nudix (nucleoside diphosphate linked moiety X) hydrolase superfamily. The encoded enzyme catalyzes the hydrolysis of modified nucleoside diphosphates, including ADP-ribose (ADPR) and 8-oxoGua-containing 8-oxo-dADP and 8-oxo-dGDP. Protein-bound ADP ribose can be hazardous to the cell because it can modify some amino acid residues, resulting in the inhibition of ATP-activated potassium channels. 8-oxoGua is an oxidized form of guanine that can potentially alter genetic information by pairing with adenine and cytosine in RNA. Presence of 8-oxoGua in RNA results in formation of abnormal proteins due to translational errors. [provided by RefSeq, Aug 2013]
Top validated antibodies |
|||||
| NSJ Bioreagents |  RQ8353 |
Polyclonal |
WB
EL
ICC
IP
IHC
FC
|
||
| Invitrogen Antibodies | PA5-112142 |
Polyclonal |
WB
EL
IP
OA
|
||
| antibodies-online | ABIN395279 |
Monoclonal |
WB
EL
IHC
|
||
| Novus Biologicals | H00011164-M04 |
Monoclonal |
WB
EL
BN
|
||
| Atlas Antibodies | HPA019827 |
Polyclonal |
WB
ICC
IHC
|
||
All Antibodies
Filters
Enhanced validation Supportive data in Antibodypedia Data presented on provider website
Data in Antibodypedia (inconclusive) Recommended by provider