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NUDT5
Nudix hydrolase 5hYSAH1, YSA1H
This gene belongs to the Nudix (nucleoside diphosphate linked moiety X) hydrolase superfamily. The encoded enzyme catalyzes the hydrolysis of modified nucleoside diphosphates, including ADP-ribose (ADPR) and 8-oxoGua-containing 8-oxo-dADP and 8-oxo-dGDP. Protein-bound ADP ribose can be hazardous to the cell because it can modify some amino acid residues, resulting in the inhibition of ATP-activated potassium channels. 8-oxoGua is an oxidized form of guanine that can potentially alter genetic information by pairing with adenine and cytosine in RNA. Presence of 8-oxoGua in RNA results in formation of abnormal proteins due to translational errors. [provided by RefSeq, Aug 2013]
Top validated antibodies |
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| NSJ Bioreagents |  RQ8353 |
Polyclonal |
WB
EL
ICC
IP
IHC
FC
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| Biorbyt | orb1743770 |
Polyclonal |
WB
EL
ICC
IP
FC
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| antibodies-online | ABIN395279 |
Monoclonal |
WB
EL
IHC
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| Novus Biologicals | H00011164-M04 |
Monoclonal |
WB
EL
BN
|
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| Invitrogen Antibodies | PA5-112142 |
Polyclonal |
WB
EL
IP
OA
|
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