TLR2

gene product
CD282, TIL4
The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. This protein is a cell-surface protein that can form heterodimers with other TLR family members to recognize conserved molecules derived from microorganisms known as pathogen-associated molecular patterns (PAMPs). Activation of TLRs by PAMPs leads to an up-regulation of signaling pathways to modulate the host's inflammatory response. This gene is also thought to promote apoptosis in response to bacterial lipoproteins. This gene has been implicated in the pathogenesis of several autoimmune diseases. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]
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1258 antibodies from 43 providers.

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AntibodyRefsTypeWBELICCIPIHCFC
Novus Biologicals
142 antibodies
Enzo Life Sciences
7 antibodies
GeneTex
31 antibodies
Abnova Corporation
31 antibodies
Acris Antibodies GmbH
45 antibodies
R&D Systems
24 antibodies
Abgent
8 antibodies
Invitrogen Antibodies
36 antibodies
Bioss
4 antibodies
Biorbyt
60 antibodies
BioLegend
38 antibodies
ABEOMICS Inc.
9 antibodies
LifeSpan BioSciences, Inc.
419 antibodies
NovoPro Bioscience Inc.
7 antibodies
OriGene
52 antibodies
Aviva Systems Biology
31 antibodies
NSJ Bioreagents
7 antibodies
Arigo
3 antibodies
Affinity Biosciences
3 antibodies
St John's Laboratory
6 antibodies
ProSci
7 antibodies
Rockland Immunochemicals, Inc.
1 antibody
Abbiotec
2 antibodies
Bioworld Technology, Inc
1 antibody
Creative Diagnostics
22 antibodies
Boster Biological Technology
3 antibodies
Cell Signaling Technology, Inc
2 antibodies
Abbexa
5 antibodies
Creative Biolabs
66 antibodies
RabMAbs
4 antibodies
BioLegend (formerly Covance Antibody Products)
2 antibodies
United States Biological
76 antibodies
MyBioSource
18 antibodies
GenWay
19 antibodies
SICGEN
1 antibody
Miltenyi Biotec
12 antibodies
eBioscience, An Affymetrix Company
36 antibodies
EMD Millipore
5 antibodies
Abiocode, Inc.
2 antibodies
RayBiotech, Inc.
5 antibodies
Abbkine Scientific Co.Ltd.
1 antibody
Sigma-Aldrich
4 antibodies
Active Motif
1 antibody